2-[4-(Trifluoromethoxy)phenyl]ethanamine

2-[4-(Trifluoromethoxy)phenyl]ethanamine - Names and Identifiers

Name	4-(Trifluoromethoxy)phenylethyl amine
Synonyms	4-(Trifluormethoxy)phenethylamine 4-(Trifluoromethoxy)phenethylamine 4-(Trifluoromethoxy)phenylethyl amine 2-[4-(Trifluoromethoxy)phenyl]ethanamine Benzeneethanamine, 4-(trifluoromethoxy)- benzeneethanamine, 4-(trifluoromethoxy)- {2-[4-(Trifluoromethoxy)phenyl]ethyl}amine 2-[4-(trifluoromethoxy)phenyl]ethan-1-amine
CAS	170015-99-3
InChI	InChI=1/C9H10F3NO/c10-9(11,12)14-8-3-1-7(2-4-8)5-6-13/h1-4H,5-6,13H2

2-[4-(Trifluoromethoxy)phenyl]ethanamine - Physico-chemical Properties

Molecular Formula	C9H10F3NO
Molar Mass	205.18
Density	1.233
Boling Point	211℃
Flash Point	81℃
Vapor Presure	0.187mmHg at 25°C
pKa	9.60±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.471

2-[4-(Trifluoromethoxy)phenyl]ethanamine - Introduction

4-(Trifluoromethoxy)phenylethyl amine is an organic compound with the chemical formula C9H10F3NO. It has some of the following properties:

Nature:
-Appearance is colorless liquid or solid
-Melting point is about 40-42 ° C
-Boiling point is about 230-231 ° C
-Soluble in organic solvents such as methanol, ethanol and chloroform
-has amino and aromatic properties

Use:
- 4-(Trifluoromethoxy)phenylethyl amine is widely used in the field of medicine, mainly as an intermediate of opioid receptor antagonists and analgesics.
-it can also be used in organic synthesis of amino reaction, aromatization reaction and fluorination reaction.

Method:
- 4-(Trifluoromethoxy)phenylethyl amine can generally be prepared by the condensation reaction of O-trifluoromethoxyphenylacetaldehyde and ethyl aminoacetate.

Safety Information:
- 4-(Trifluoromethoxy)phenylethyl amine is less toxic, but it still needs to be used carefully to avoid inhalation, intake or contact with skin and eyes.
-During use, personal protective measures should be taken, such as wearing gloves, eye protection and breathing apparatus.
-When storing, keep away from fire and oxidizing agents and keep the storage container sealed.
-If you come into contact with this substance, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 15:17:53